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| website = | spouse = Susan Jennifer Barfield〔 | children = one son, one daughter〔 }} Denis Noble CBE FRS FRCP FMedSci (born 16 November 1936) is a British biologist who held the Burdon Sanderson Chair of Cardiovascular Physiology at the University of Oxford from 1984 to 2004 and was appointed Professor Emeritus and co-Director of Computational Physiology. He is one of the pioneers of Systems Biology and developed the first viable mathematical model of the working heart in 1960.〔(Biography ), Denis Noble homepage.〕 ==Education== Noble was educated at Emanuel School and University College London (UCL).〔〔 In 1958 he began his investigations into the mechanisms of heartbeat. This led to two seminal papers in ''Nature'' in 1960〔〔 giving the first proper simulation of the heart. From this work it became clear that there was not a single oscillator which controlled heartbeat, but rather this was an emergent property of the feedback loops in the various channels. In 1961 he obtained his PhD working under the supervision of Otto Hutter at UCL.〔Dennis Noble (2006). ''The Music of Life'', ISBN 0-19-929573-5〕 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Denis Noble」の詳細全文を読む スポンサード リンク
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